Nucleoside deaminase activity in viral leukemia.

作者: V. G. Malathi , Ivan K. Rothman , Robert Silber

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摘要: Summary Nucleoside deaminase activity was determined following inoculation of mice with several leukemia viruses. The erythroblastic disorders induced by Friend virus and Rauscher were associated markedly elevated levels spleen nucleoside deaminase. High enzyme also found in transplantable solid tumors tissue culture lines derived from virus-induced leukemia. lymphocytic resulting Moloney infection did not lead to alterations the level It is suggested that appearance during leukemogenesis a reflection erythroid nature these disorders.

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