To normalize or not to normalize? Fat is the question

作者: Craig E. Hebert , Karen A. Keenleyside

DOI: 10.1002/ETC.5620140509

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摘要: Concentrations of lipophilic contaminants in biota are frequently corrected for variation tissue lipid content. Usually, this correction is accomplished by dividing contaminant concentration to form lipid-normalized data. This ratio-based approach satisfactory when varies direct proportion However, such a relationship does not exist, erroneous conclusions may be reached. Recent research has emphasized the potential shortcomings use ratio variables. We demonstrate importance considering these lipid-normalizing Three examples presented, and an alternative based upon analysis covariance (ANCOVA) suggested.

参考文章(16)
Robert V. Thomann, John P. Connolly, Model of PCB in the Lake Michigan lake trout food chain Environmental Science & Technology. ,vol. 18, pp. 65- 71 ,(1984) , 10.1021/ES00120A003
David S. DeVault, Wayne A. Willford, Robert J. Hesselberg, David A. Nortrupt, Eric G. S. Rundberg, Alwan K. Alwan, Cecilia Bautista, Contaminant trends in lake trout ( Salvelinus namaycush ) from the Upper Great Lakes Archives of Environmental Contamination and Toxicology. ,vol. 15, pp. 349- 356 ,(1986) , 10.1007/BF01066401
Robert V. Thomann, John P. Connolly, Thomas F. Parkerton, An equilibrium model of organic chemical accumulation in aquatic food webs with sediment interaction Environmental Toxicology and Chemistry. ,vol. 11, pp. 615- 629 ,(1992) , 10.1002/ETC.5620110505
R. J. Pruell, N. I. Rubinstein, B. K. Taplin, J. A. LiVolsi, R. D. Bowen, Accumulation of Polychlorinated Organic Contaminants from Sediment by Three Benthic Marine Species Archives of Environmental Contamination and Toxicology. ,vol. 24, pp. 290- 297 ,(1993) , 10.1007/BF01128727
Joseph Camanzo, Clifford P. Rice, David J. Jude, Ronald Rossmann, Organic Priority Pollutants in Nearshore Fish from 14 Lake Michigan Tributaries and Embayments, 1983 Journal of Great Lakes Research. ,vol. 13, pp. 296- 309 ,(1987) , 10.1016/S0380-1330(87)71653-0
John P. Connolly, Chrissa J. Pedersen, A thermodynamic-based evaluation of organic chemical accumulation in aquatic organisms Environmental Science & Technology. ,vol. 22, pp. 99- 103 ,(1988) , 10.1021/ES00166A011
Craig E. Hebert, G. D. Haffner, Habitat Partitioning and Contaminant Exposure in Cyprinids Canadian Journal of Fisheries and Aquatic Sciences. ,vol. 48, pp. 261- 266 ,(1991) , 10.1139/F91-036
John D. Schell, Dean M. Campbell, Edgar Lowe, Bioaccumulation of 2,3,7,8-tetrachlorodibenzo-P-dioxin in feral fish collected from a bleach-kraft paper mill receiving stream Environmental Toxicology and Chemistry. ,vol. 12, pp. 2077- 2082 ,(1993) , 10.1002/ETC.5620121115
William R. Atchley, Charles T. Gaskins, Dwane Anderson, Statistical Properties of Ratios. I. Empirical Results Systematic Biology. ,vol. 25, pp. 137- 148 ,(1976) , 10.2307/2412740