Linear and nonlinear analysis of heart rate variability during propofol anesthesia for short-duration procedures in children.

摘要: OBJECTIVE To determine whether heart rate variability metrics provide an accurate method of monitoring depth anesthesia, assessing the response to painful stimuli, and neuroautonomic regulation cardiac activity in children receiving propofol anesthesia for short-duration procedures. DESIGN Prospective, case series. SETTING Sixteen-bed pediatric intensive care unit, oncology endoscopy suite a tertiary children's hospital ophthalmology examination rooms associated eye institute. PATIENTS Thirty-three patients undergoing short INTERVENTIONS None. MEASUREMENTS AND MAIN RESULTS Heart studied included mean, SD, low- high-frequency power, detrended fluctuation analysis (represented by correlation coefficient, alpha), approximate entropy. Compared with initial anesthetized state, we found increased SD (3.17 +/- 1.31 vs. 7.05 0.26 bpm, p <.0001), low-frequency power (3.69 0.36 4.48 0.41 bpm(2)/Hz, low-/high-frequency ratio (1.47 1.26 0.24, =.001), alpha (1.12 0.24 1.35 0.21, <.0001) during procedure. Mean (105.8 13.4 101.5 12.4 =.005) entropy decreased procedure (0.75 0.19 0.53 + 0.16, <.001), whereas there was no significant change (3.04 0.63 3.16 0.71 =.26). CONCLUSIONS We conclude that spectral may be clinically useful measure anesthesia. speculate correlates allows assessment patient's sympathetic pain.