Evaluation of changes in hemoglobin levels associated with ABO-incompatible plasma in apheresis platelets.

摘要: Background Hemolytic transfusion reaction is considered a rare complication of platelet transfusion. If minor ABO incompatibility exists (donor antibody directed against recipient's red cells [plasma-incompatible platelets]), however, the antibodies present in plasma platelets may cause acute hemolysis. A retrospective study was performed to identify possible hemolysis related plasma-incompatible apheresis platelets. Study design and methods Acute due low-titer anti-A group O transfused patient reported. Pretransfusion posttransfusion hemoglobin levels were evaluated 16 non-group autologous bone marrow transplant patients receiving All received, within 24 hours, both ABO-identical transfusions. No during time between collection pretransfusion samples. Results total evaluable paired transfusions compared. The mean change following -0.50 g per dL -0.11 dL, respectively (p = 0.193). Conclusion There no significant concentration associated with (minor incompatibility) our group. case reported here represents only hemolytic identified among 46,176 at this hospital, despite approximately 21 percent all being incompatible. risk such remains low.