Hyaluronic acid-modified Fe3O4@Au core/shell nanostars for multimodal imaging and photothermal therapy of tumors
作者： Jingchao Li , Yong Hu , Jia Yang , Ping Wei , Wenjie Sun
DOI: 10.1016/J.BIOMATERIALS.2014.10.065
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摘要: Abstract Development of multifunctional theranostic nanoplatforms for diagnosis and therapy of cancer still remains a great challenge. In this work, we report the use of hyaluronic acid-modified Fe 3 O 4@ Au core/shell nanostars (Fe 3 O 4@ Au-HA NSs) for tri-mode magnetic resonance (MR), computed tomography (CT), and thermal imaging and photothermal therapy of tumors. In our approach, hydrothermally synthesized Fe 3 O 4@ Ag nanoparticles (NPs) were used as seeds to form Fe 3 O 4@ Au NSs in the growth solution. Further …
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