De novo and recurrent membranous glomerulopathy following kidney transplantation.

摘要: Membranous glomerulopathy, de novo or recurrent, in the allograft kidney is a recognized, albeit uncommon, clinical entity. We examined records of 936 renal recipients seven and one-half year period. De membranous glomerulopathy developed six patients. The mean onset nephrotic-range proteinuria after transplantation was at 18.1 months (with range from 4 to 30 months). did not adversely affect graft survival. Twenty-five patients were transplanted for end-stage disease caused by glomerulopathy. rate recurrence who lose their rejection immediate posttransplant period 7%. Additional prednisone therapy standard immunosuppressive protocol appear be beneficial. One patient, original lesion, received an HLA-identical kidney. Onset occurred four weeks post-transplant. Recurrent has been reported five other In two living related allografts within transplant. Patients with receive allograft, especially one that HLA-identical, may higher risk morbidity early recurrence. recommend caution use transplant