Prevalence and long-term outcome of glomerulonephritis in renal allografts.

作者: Hans-Hellmut Neumayer , Mirjam Kienbaum , Stephan Graf , Mathias Schreiber , Johannes F.E. Mann

DOI: 10.1016/S0272-6386(12)70325-6

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摘要: We report long-term results over 10 years in patients developing glomerulonephritis after renal transplantation. The prevalence rate of was 6.2% 785 transplants involving 697 with end-stage disease. This 14% undergoing biopsy their grafts because malfunction. 15% diagnosed as having any cause prior to Membranous, focal sclerosing, and IgA were the most common histologic diagnoses. Documented recurrence occurred only 1% prior, biopsy-proven native kidneys. Patients sclerosing had greatest risk from recurrence. De novo likely be membranous character. graft survival not distinguishable that showing rejection; both 45% at 60 months 33% versus 11 %, respectively, 120 ( P = NS); without rejection 76% months. Thus, is responsible for approximately Glomerulonephritis has a prognosis similar chronic rejection. Finally, specific unusual. should discouraged transplantation putative risks related

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