Graft Loss Due to Recurrent Focal Segmental Glomerulosclerosis in Renal Transplant Recipients in the United States
作者： Kevin C. Abbott , Eric S. Sawyers , James D. Oliver , Chia W. Ko , Allan D. Kirk
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摘要: Rates of and risk factors for graft loss resulting from recurrent focal segmental glomerulosclerosis (FSGS) have not been studied in a national population. A retrospective analysis was performed on registry (1999 United States Renal Data System) 101,808 renal transplant recipients (October 1, 1987, to December 31, 1996). Of these, 3,861 solitary transplants who had end-stage disease FSGS met inclusion criteria. Outcomes were FSGS. As percentage all loss, accounted 18.7% living donor 7.8% cadaveric recipients. In white recipients, the corresponding figures 27% 13%. multivariate analysis, associated with recipient, African-American kidney younger recipient age, treatment rejection. higher rates overall. superior overall survival. Among FSGS, disproportionately seen kidneys. The role donor/recipient race pairing should be validated. Living no association after correction other factors. may most gain donor, given their improved survival decreased This is US government work. There are restrictions its use.
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