Estrogen receptor genotypes and their association with the 10-year changes in bone mineral density and osteocalcin concentrations.
作者： MaryFran Sowers , Mary L. Jannausch , Wei Liang , Marcia Willing
关键词:
摘要: We conducted a 10-yr prospective study of peak bone mass and its change in 604 women, aged 24–44 yr at initiation, related changes mineral density (BMD) osteocalcin (OCN) concentrations to estrogen receptor (ER) α gene polymorphisms 442 these women. examined the association ERα PvuII XbaI with lumbar spine (LS) femoral neck (FN) BMD, measured by densitometry, as well serum OCN levels, after accounting for weight menstrual status change. The women were members Michigan Bone Health Study, population-based longitudinal BMD. There was linear loss LS BMD curvilinear FN from over period. Women homozygous variant without an restriction site (XbaI −/− genotype) had higher less time. (PvuII time ...
oup.com
endojournals.org参考文章(34)
Christine M. Snow-Harter, Bone health and prevention of osteoporosis in active and athletic women. Clinics in Sports Medicine. ,vol. 13, pp. 389- 404 ,(1994) , 10.1016/S0278-5919(20)30337-9
JAMES F. SALLIS, WILLIAM L. HASKELL, PETER D. WOOD, STEPHEN P. FORTMANN, TODD ROGERS, STEVEN N. BLAIR, RALPH S. PAFFENBARGER, PHYSICAL ACTIVITY ASSESSMENT METHODOLOGY IN THE FIVE-CITY PROJECT American Journal of Epidemiology. ,vol. 121, pp. 91- 106 ,(1985) , 10.1093/OXFORDJOURNALS.AJE.A113987
MaryFran R. Sowers, Anant Kshirsagar, Mary M. Crutchfield, Sharon Updike, Joint Influence of Fat and Lean Body Composition Compartments on Femoral Bone Mineral Density in Premenopausal Women American Journal of Epidemiology. ,vol. 136, pp. 257- 265 ,(1992) , 10.1093/OXFORDJOURNALS.AJE.A116491
M. Revilla, L.F. Villa, E.R. Hernandez, A. Sanchez-Atrio, J. Cortes, H. Rico, Influence of weight and gonadal status on total and regional bone mineral content and on weight-bearing and non-weight-bearing bones, measured by dual-energy X-ray absosorptiometry Maturitas. ,vol. 28, pp. 69- 74 ,(1997) , 10.1016/S0378-5122(97)00050-9
Geert Molenberghs, Geert Verbeke, Linear Mixed Models for Longitudinal Data ,(2000)
J.P. Brown, L. Malaval, M.C. Chapuy, P.D. Delmas, C. Edouard, P.J. Meunier, SERUM BONE GLA-PROTEIN: A SPECIFIC MARKER FOR BONE FORMATION IN POSTMENOPAUSAL OSTEOPOROSIS The Lancet. ,vol. 323, pp. 1091- 1093 ,(1984) , 10.1016/S0140-6736(84)92506-6
D. J. Hunter, M. de Lange, T. Andrew, H. Snieder, A. J. MacGregor, T. D. Spector, Genetic variation in bone mineral density and calcaneal ultrasound : A study of the influence of menopause using female twins Osteoporosis International. ,vol. 12, pp. 406- 411 ,(2001) , 10.1007/S001980170110
MaryFran R. Sowers, Michael Boehnke, Mary L. Jannausch, Mary Crutchfield, Genie Corton, Trudy L. Burns, Familiality and partitioning the variability of femoral bone mineral density in women of child-bearing age Calcified Tissue International. ,vol. 50, pp. 110- 114 ,(1992) , 10.1007/BF00298785
RUSSELL T. TURNER, B. LAWRENCE RIGGS, THOMAS C. SPELSBERG, Skeletal Effects of Estrogen Endocrine Reviews. ,vol. 15, pp. 275- 300 ,(1994) , 10.1210/EDRV-15-3-275
Clinton T. Rubin, Lance E. Lanyon, Regulation of bone mass by mechanical strain magnitude Calcified Tissue International. ,vol. 37, pp. 411- 417 ,(1985) , 10.1007/BF02553711