作者: Shenglin Qiao , Hao Wang
DOI: 10.1007/S12274-018-2121-X
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摘要: Interest in temperature-responsive polymers has steadily grown over the past several decades, and numerous studies have been dedicated to developing temperature sensitive that can be constructed into new smart materials for biomedical applications. Phase behavior of a polymer plays pivotal role determining its biological performance certain conditions. In addition additives (such as salts proteins) aqueous solutions, molecular weight, weight distribution, structural or compositional factors also significantly affect transition temperatures polymers. This review comprehensively describes well-established newly developed synthetic strategies preparing The parameters self-assembly are discussed. Finally, applications drug delivery, immunotherapy, tissue engineering, diagnosis summarized.