Dummy run for a phase II study of stereotactic body radiotherapy of T1-T2 N0M0 medical inoperable non-small cell lung cancer

摘要: In forthcoming multicentre studies on stereotactic body radiotherapy (SBRT) compliance with volume and dose prescriptions will be mandatory to avoid unnecessary heterogeneity bias. To evaluate in a setting we used two cases from an ongoing phase II study of SBRT T1-T2N0M0 inoperable NSCLC dummy run oriented volumes doses. Six Scandinavian centres participated. Each centre received CT-scans covering the whole lung patients instructions follow protocol when outlining tumour target volumes, prescribing doses creating plans. Volumes 12 plans were evaluated according protocol. For GTV range was 24 39 cm3 26 41 cm3, respectively. The PTV 90 116 cm3, 112 155 cm3, all margin between CTV directions followed detail prescribed for 45 Gy/3 fractions (is...