Stereochemistry of reduction of cyclic ketones by alkali metals and by sodium dithionite.
作者： Graziano Castaldi , Giulio Perdoncin , Claudio Giordano , Francesco Minisci
DOI: 10.1016/S0040-4039(00)81962-0
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摘要: Abstract An opposite stereoselectivity is observed in the reduction of 3α-hydroxy-5β-7-oxo-cholanic acid by alkali metals and sodium dithionite, contrary to results reported with other cyclic or bicyclic ketones. electron-transfer mechanism followed coupling ketyl radical suggested for dithionite.
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