Chronic hepatitis B: management challenges in resource-poor countries.

作者: Sylvester Chuks Nwokediuko

DOI: 10.5812/KOWSAR.1735143X.757

关键词:

摘要: Sylvester Chuks Nwokediuko, Department of Medicine, University Nigeria Teaching Hospital, Ituku OzallaChronic infection with hepatitis B virus (HBV) is a global public health problem because its worldwide distribution and potential to cause sequelae. HBV most prevalent in China, South East Asia, sub-Saharan Africa, the Amazon basin America where care resources are limited. Numerous challenges exist for effective management chronic infection, particularly resource-limited regions. These include lack accurate prevalence data, absence surveillance program, poor political will governments resource-poor countries enforce measures control disease. There understanding regarding infec-tion by both general providers. A better pathogenesis treatment this condition necessary. The acute shortage trained medical manpower necessary diagnosis hepati-tis (CHB) formidable challenge. com-plicated continuing efflux graduates from low-income economies richer countries. critical CHB high cost laboratory tests drugs. Drugs also not readily available. Other manage-ment stigmatization patients, co-infection other viruses, guidelines, an patient referral system. To address these challenges, nations must be committed budg-etary allocation implementation programs. It provide awareness campaigns, education, proper screening blood products transfusion, active screening, intensification existing childhood immunization, technical financial assistance wealthier nations, recommendations outlined Global Hepatitis Policy (2010).

参考文章(65)
Goldin Rd, Thursz M, Ndububa Da, Adeodu Oo, Akonai Ak, Ojo Os, Fatusi Oa, Durosinmi Ma, Hepatitis D virus antigen in HBsAg positive chronic liver disease in Nigeria. East African Medical Journal. ,vol. 75, pp. 329- 331 ,(1998)
U. O. Amazigo, A. B. Chime, Hepatitis-B virus infection in rural and urban populations of eastern Nigeria: prevalence of serological markers. East African Medical Journal. ,vol. 67, pp. 539- 544 ,(1990)
Iseniyi Jo, Olatunji Po, Onile Ba, Adewuyi Jo, Bada As, Hepatitis B surface antigenaemia in Ilorin, Kwara State, Nigeria. The Central African journal of medicine. ,vol. 42, pp. 139- 141 ,(1996)
W H Foege, D L Eddins, Mass vaccination programs in developing countries. Progress in medical virology. Fortschritte der medizinischen Virusforschung. Progres en virologie medicale. ,vol. 15, pp. 205- 243 ,(1973)
J. M. Oli, G. O. Okafor, The prevalence of hepatitis B surface antigen in Nigerian diabetics. Tropical and geographical medicine. ,vol. 32, pp. 40- 44 ,(1980)
Zaffran M, Simonsen L, Lloyd J, Kane A, Kane M, Unsafe injections in the developing world and transmission of bloodborne pathogens: a review. Bulletin of The World Health Organization. ,vol. 77, pp. 789- 800 ,(1999)
U Ijeoma, SC Nwokediuko, Seroprevalence of antibody to HDV in Nigerians with hepatitis B virus-related liver diseases. Nigerian Journal of Clinical Practice. ,vol. 12, pp. 439- ,(2009) , 10.4314/NJCP.V12I4.54646
Elke Wiseman, Melissa A Fraser, Sally Holden, Anne Glass, Bronwynne L Kidson, Leon G Heron, Michael W Maley, Anna Ayres, Stephen A Locarnini, Miriam T Levy, Perinatal transmission of hepatitis B virus: an Australian experience. The Medical Journal of Australia. ,vol. 190, pp. 489- 492 ,(2009) , 10.5694/J.1326-5377.2009.TB02524.X
R. PALMER BEASLEY, CHRISTIAN TREPO, CLADD E. STEVENS, WOLF SZMUNESS, THE e ANTIGEN AND VERTICAL TRANSMISSION OF HEPATITIS B SURFACE ANTIGEN American Journal of Epidemiology. ,vol. 105, pp. 94- 98 ,(1977) , 10.1093/OXFORDJOURNALS.AJE.A112370
D. A. Henderson, William H. Foege, J. D. Millar, Smallpox eradication in West and Central Africa. Bulletin of The World Health Organization. ,vol. 52, pp. 209- 222 ,(1975)