Epigenetic polypharmacology: A new frontier for epi-drug discovery.

作者: Daniela Tomaselli , Alessia Lucidi , Dante Rotili , Antonello Mai

DOI: 10.1002/MED.21600

关键词:

摘要: … two potent and selective PRMT5 inhibitors that induced tumor … Two HDAC/TK dual inhibitors entered clinical trials for … ) and BRD4 are key targets in AML,295 and both BRD4 and JAK …

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