Comparison of bioactive glass, mineral trioxide aggregate, ferric sulfate, and formocresol as pulpotomy agents in rat molar

摘要: Bioactive glass (BAG) is often used as a filler material for repair of dental bone defects. Although there evidence osteogenic potential this material, it not clear yet whether the exhibits dentinogenesis. Hence, aim present study was to evaluate BAG pulpotomy agent and compare with three commercially available agents such formocresol (FC), ferric sulfate (FS), mineral trioxide aggregate (MTA). Pulpotomies were performed in 80 maxillary first molars Sprague Dawley rats, pulp stumps covered BAG, FC, FS, MTA. Histologic analysis at 2 weeks then 4 after treatment. Experimental samples compared contra-lateral normal molars. At weeks, showed inflammatory changes pulp. After some histology, vasodilation. MTA acute cells around macrophages radicular Dentine bridge formation histology consistent finding Ferric moderate inflammation widespread necrosis coronal weeks. Formocresol zones atrophy, inflammation, fibrosis. Fibrosis more extensive calcification certain samples. Among materials tested, ideally causing dentine while simultaneously maintaining pulpal histology. It appeared that induced an response resolution