The scientific work of Peter Bauer

摘要: This June, Peter Bauer – chief editor of Biometrical Journal from 2000–2003 and member the editorial board since 1996 celebrated his 65th birthday. became known as one originators “adaptive designs”, a field research that recently gained considerable popularity, not only among academia but likewise regulatory bodies pharmaceutical industry. It is characteristic for Bauer, while designs” make their way into main stream statistics, he already on search new challenges now works, others, statistical problems relevant to bioinformatics. His sense dynamic areas can be easily seen whole professional career where covered wide range fields including informatics, binomial poisson processes, model robustness, optimal designs, multiple testing, sequential analysis, adaptive designs started scientific at medical faculty University Vienna, was appointed 1985 head Department Medical Documentation Statistics in Cologne returned Vienna 1994 become faculty. Besides co-operation many clinical projects built up an active group. He currently decided accept lead Core Unit Informatics, superordinate unit several other departments independent university 2004. In view proceeding structural changes taking this just more example persistent willingness explore challenges. As physicist by education, part pioneering epoch computer science Vienna. late sixties developed programming language chemical reactions worked based diagnostic programs liverdiseases. Confronted with need expertise faculty, turned statistics British Council Research Fellow Edinburgh David Finney department time. fascinated school got involved challenging consulting were starting point methodological papers. Motivated practical experience high dimensional compartment models method specify power discrimination between different regression investigated related design concept nowadays T-optimality. The published two papers “Biometrische Zeitschrift” (Bauer, 1975a, b) year before journal renamed “Biometrical Journal”. Another practically oriented analysis cross-sectional study caries protective effects fluorid. To hazard occurrence forestalled development frailty (Bauer et al., 1980, 1982). fruitful cooperation Hackl contributed theory quality control testing. first paper comparisons Hackl, 1985). multiplicity issue inference subject subsequent works applications dose finding (e.g. Budde 1989; Budde, 1994; 1998; Brannath Posch, 2000), selection P tscher 1988), equivalence testing 1994)