Cutaneous squamous cell carcinoma associated with proliferation of osteoclast-like giant cells.

摘要: Proliferation of osteoclast-like giant cells in a cutaneous squamous cell carcinoma is rare phenomenon and so far only four cases have been reported. In previous reports, were admixed with sarcomatoid component it therefore debatable if the represent reactive or part malignant tumour. A case associated However, sarcomatous was not identified this case. Morphologically, osteloclast-like appeared to be benign. The localization osteoclastic-like separate from one another. Immunohistochemically, positive for high molecular weight cytokeratin, cytokeratin-5 p63, whereas histiocyte marker CD68 vimentin negative epithelial markers supporting nature malignancy.