The development of cervical cancer and its precursors: what is the role of human papillomavirus infection?

摘要: Human papillomavirus (HPV) is a significant health care burden in the United States. The majority of sexually active men and women will be infected with HPV at some point their lives are subject to developing human papillomavirus-associated disease. Current estimates suggest that 20 million Americans currently infected, more than 5 new infections occur each year. prevalence highest populations late teens early twenties, nearly half all occurring within 3 years first intercourse. necessary cause genital warts, cervical intraepithelial neoplasia, invasive cancer. As such, responsible for medical morbidity costs. Screening cytology has significantly reduced mortality rates; however, approximately 3900 die 2005 from cancer DNA testing shown promise identifying high-grade abnormalities as an adjunct traditional cytology, should used according guidelines established by American Cancer Society College Obstetricians Gynecologists. epidemiology infection brief introduction natural history presented here.