The role of drinking and cigarette smoking in the excess deaths from liver cancer.

摘要: A long-term cohort study of 639 males in a farming area and 677 fishing Kyushu, Japan, has been conducted to evaluate risk factors for ischemic heart disease. The present investigation utilized this assess the role drinking cigarette smoking habits causation liver cancer. O/E ratio (ratio observed expected number deaths) cancer was 7.5 (P less than 0.001) among shochu drinkers area. Further, clear dose-response relationship noted: 5.7 0.001), 20.0 1, 1-2, 2 or more units (a distilled alcoholic beverage made Japan; about 25% alcohol). Although no excess found area, numbers were too small make valid judgements. Among sake drinkers, very similar both areas. Cigarette smokers appeared have high cancer, being 4.8 0.001). However, there ratios according their indicated nondrinkers. multiple logistic regression analysis showed an insignificant effect on development after adjustment drinking. These findings suggest significant involvement etiology at least