Tongue carcinoma infrequently harbor common actionable genetic alterations

作者: Daniel SW Tan , Weining Wang , Hui Sun Leong , Pui Hoon Sew , Dawn P Lau

DOI: 10.1186/1471-2407-14-679

关键词:

摘要: Background Oral tongue squamous cell carcinomas (TSCC) are a unique subset of head and neck cancers with distinct demographic profile, where up to half the cases never smokers. A small proportion patients OSCC known respond EGFR TKI. We used high-sensitivity mass spectrometry-based mutation profiling platform determine status, as well other actionable alterations in series Asian TSCC.

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