Aldehyde oxidase-catalysed oxidation of methotrexate in the liver of guinea-pig, rabbit and man.

作者: C. GERALDINE M. JORDAN , MOHAMMED R. RASHIDI , HUSSAIN LALJEE , STEPHEN E. CLARKE , JOHN E. BROWN

DOI: 10.1211/0022357991772619

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摘要: … White rabbit liver Methotrexate (50 mg) was dissolved in a minimum amount of 0¡1M NaOH. … adjusted to 7¡8 with 5M NaOH initially and then 0¡5M NaOH. The enzyme used was partially …

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