Evaluation of Serum Adenosine Deaminase as a Tumor Marker in Gastric Cancer

作者: Srinivasa Rao , Aparna R.Bitla

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摘要: Currently re c o mmended tumor markers in gas tric cancer are being used to monitor treatment or detect recurrences and serum a rc oembryonic antigen (CEA) is widely accepted marker the management of cancer. Hence there n e d for identifying which will be useful detecting Alt ra t io ns enzyme levels well known, adenos ine deaminase (ADA), an purine salvage pathway, has been found elev v rio u s malignancies . The present tudy was carried out on 30 healthy controls 22 patients ADA seru m es timated by colorimetric method Galanti Gius ti. diagnos tic accuracy assessed receiver operating ch ris tics (ROC) curves relevance independent two combination wa nalyzed logis regress ion model. Increase (p<0.001) CEA (p<0.005) activity p ie when compared Areas under ROC rv we 0.908 ADA, 0.865 CEA. area curve both were combined 0.952. have trong predictor outcome hence may cons idered as potential

参考文章(4)
Bansal A, Agrawal Ak, Joshi Ld, Bansal Sk, Narang Rk, Singh Rp, Serum adenosine deaminase in pulmonary tuberculosis, malignancy and non-tubercular respiratory diseases. The Indian journal of chest diseases & allied sciences. ,vol. 33, pp. 189- 193 ,(1991)
A Eroĝlu, O Canbolat, S Demirci, H Kocaoĝlu, Y Eryavuz, H Akgül, Activities of adenosine deaminase and 5'-nucleotidase in cancerous and noncancerous human colorectal tissues. Medical Oncology. ,vol. 17, pp. 319- 324 ,(2000) , 10.1007/BF02782198
M. EARL BALIS, Adenosine deaminase and malignant cells. Annals of the New York Academy of Sciences. ,vol. 451, pp. 142- 149 ,(1985) , 10.1111/J.1749-6632.1985.TB27105.X
Ozturan O, Kizilay A, Güleç M, Akyol O, Kalcioğlu Mt, Yilmaz Hr, Uz E, Adenosine deaminase, xanthine oxidase, superoxide dismutase, glutathione peroxidase activities and malondialdehyde levels in the sera of patients with head and neck carcinoma. KBB Journal of ear, nose, and throat. ,vol. 12, pp. 16- 22 ,(2004)