摘要: Bleomycin, busulphan, and methotrexate are by far the commonest cytotoxic drugs to cause interstitial pneumonitis. However, many other have been reported produce similar lung damage. Combined effects of these drugs, with agents that damage, such as oxygen radiation, may result in enhancement Early diagnosis, made possible awareness this complication its correct investigation, reduce severe morbidity mortality. In some instances, factors predispose damage known, studied experimental animals.