摘要: Editor,—In his leading article Hills reviews important concepts about a “hydrophobic mucosal barrier” as the main biological basis for protecting stomach against acid mediated damage to mucosa ( Gut 1996; 39: 621–4). While we support author’s view that lipid rather than mucus makes gastric surface less vulnerable protons, proposed analogy of this with lung surfactant is supported by little direct evidence. claims key molecule surfactant, dipalmitoyl phosphatidylcholine (DPPC), also factor based on indirect measurements some 20 years ago.1 Editor,—In …
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