作者: A.J. Wester
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摘要: In addiction care, most individuals seeking help do have problems in alcohol use. However, prolonged use, may cause damage to the brain, potentially producing cognitive deficits that range from mild a alcohol-related dementia (ARD). These impairments probably, be attributed direct neurotoxicity of alcohol. Brain structures appear vulnerable effects are neocortex, limbic system, hippocampus and cerebellum. combination with malnutrition, resulting thiamine deficiency, Korsakoff syndrome result as well. Neuropathological changes concern petechial haemorrhaging, specifically corpora mammillaria, thalamus, various around third fourth ventricles. is characterized by severe amnesia, especially anterograde executive dysfunction. clinical practice, delineating or difficult, for all these conditions clear biomarkers date lacking. Moreover, abnormalities brain supposed underlie cannot easily detected conventional imaging techniques. Lastly, syndromal diagnosis without discrete neuroanatomical substrate. Also, consensus on criteria ARD, he which never been fully accepted, changing. Nevertheless, thorough analysis psychological functioning individual patients alcohol-use disorders, always recommended.