Camptocormia as a clinical manifestation of polymyositis/systemic sclerosis overlap myositis associated with anti-Ku

摘要: Camptocormia, an abnormal truncal flexion posture that occurs while walking or standing, is usually caused by various hypokinetic movement disorders, mainly Parkinson disease. We describe the case of a man with subacute onset camptocormia. Quadriceps muscle biopsy showed significant rhabdomyolysis, few isolated inflammatory cells and mild expression type I MHC in fibers, pattern found immune-mediated necrotizing myopathies. Myositis was associated Raynaud’s phenomenon, sclerodactyly, anti-Ku antibodies leading to diagnosis polymyositis/systemic sclerosis overlap myositis. The modest improvement response treatment.