Hyperoxia and red cell 2,3-diphosphoglycerate☆

作者: Joseph B. Weissberg , James D. Crapo

DOI: 10.1016/0041-008X(76)90025-9

关键词:

摘要: Abstract Elevated oxygen tensions were shown to result in the decline of red cell 2,3-diphosphoglycerate (2,3-DPG) 3- and 4-week-old rats. A decrease 2,3-DPG was observed after 6 hr exposure 100% maximal at 24–36 hr. The effect persisted throughout a 7-day period. Recovery normal values occurred within 10 removal from hyperoxic exposure. Concentrations 40, 60, 80% also induced 2,3-DPG. hyperoxia on found change with age. No concentrations rats older than 4 weeks. animals be less tolerant toxic effects oxygen.

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