Detection of cervical neoplasia--reducing the risk of error.

摘要: In cytology studies false negative smears range from 1.8% to 20% due different levels of cytologic expertise and material presented the pathologist. Only 6% in situ carcinomas cervix have an abnormal gross appearance so routine multiple biopsies are needed. Schillers test using a weak aqueous solution iodine leaves area carcinoma unstained but colors normal cervical epithelium dark brown. However not all areas which fail stain represent foci cancer. Multiple endocervical curettage required particularly detect lesions involving portio. Conization is most accurate method for evaluating suspicious cervix. 80 histo logic sections should be examined each specimen. Complicati ons conization may hemorrhage stenosis uterine perforation pelvic infection. after 4-6 weeks does infection cease significant risk. When done during pregnancy cause fetal loss 15%. Colposcopy has low false-negative rate cannot inside canal. It best clinical evaluation patients with cytological pregnancy. A colposcopic diagnosis based on vascular pattern intercapillary distance surface contour color tone clarity demarcation. Where examination unsatisfactory positive indicated. The final depends histology directed biopsy.