Acute Cellular Rejection

摘要: Acute cellular rejection (ACR) is the consequence of an immune response host against kidney graft. It clinically suspected in patients experiencing increase serum creatinine, after exclusion other causes graft dysfunction (generally with biopsy). Histological analysis biopsy gold standard technique to diagnose ACR. However, can recognize reaction only at its later stages, when allograft injury has already been established. Therefore, identification noninvasive biomarkers capable identifying early signs acute represents area intense research. ACR often treatable, but it still adverse risk factor affecting long-term survival. The occurrence episodes modern transplantation should always elicit a search for underimmunosuppression relative what understood as given recipient’s Importantly, patient adherence therapy be carefully addressed.