Preoperative mediastinal and hilar nodal staging with diffusion-weighted magnetic resonance imaging and fluorodeoxyglucose positron emission tomography/computed tomography in patients with non–small-cell lung cancer: Which is better?

摘要: Abstract Background To compare the diagnostic capability of diffusion-weighted magnetic resonance imaging (DWI) and 18 F-fluorodeoxyglucose positron emission tomography/computed tomography ( F-FDG PET/CT) in N stage assessment patients with non–small-cell lung cancer. Methods We performed a meta-analysis all available studies performance DWI PET/CT determined sensitivity specificity across studies, calculated positive negative likelihood ratios (LR+ LR−, respectively), constructed summary receiver operating characteristic curves using hierarchical regression models. The methodologic quality was assessed Quality Assessment Diagnostic Accuracy Studies tool. Results A total 19 met inclusion criteria included 2845 pathologically confirmed patients. No publication bias found. relatively high. pooled estimate (0.72, 95% confidence interval [CI] 0.63–0.80) not significantly difference between (0.75, CI 0.68–0.81; P = 0.09). for (0.95, 0.85–0.98) greater than (0.89, 0.85–0.91; 0.02). For DWI, overall LR+ 13.80 (95% 4.54–41.95) LR− 0.29 0.21–0.40). PET/CT, 6.67 5.20–8.56) 0.28 0.22–0.37). Conclusions Our study has that high staging cancer compared potential to be reliable alternative noninvasive method preoperative mediastinal hilar lymph nodes