The JAK2 46/1 haplotype: a marker of inappropriate myelomonocytic response to cytokine stimulation, leading to increased risk of inflammation, myeloid neoplasm, and impaired defense against infection?

作者: S. Hermouet , M. Vilaine

DOI: 10.3324/HAEMATOL.2011.055392

关键词:

摘要: The 46/1 haplotype of chromosome 9p, present in about 45% the general population, is associated with a predisposition to mutations Janus Kinase 2 ( JAK2 ) gene on same allele and chronic myeloproliferative neoplasms (MPN): polycythemia vera, essential thrombocythemia primary

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