Dissolution and bioavailability improvement of bioactive apigenin using solid dispersions prepared by different techniques.

作者: Sultan M. Alshehri , Faiyaz Shakeel , Mohamed A. Ibrahim , Ehab M. Elzayat , Mohammad Altamimi

DOI: 10.1016/J.JSPS.2018.11.008

关键词:

摘要: … ml of purified water with 1% … DSC spectra obtained in this study with literature values of APG. The single and crystalline endothermic peak of pure APG suggested that APG exists in pure …

参考文章(61)
Buyun Ding, Hao Chen, Chao Wang, Yingjie Zhai, Guangxi Zhai, Preparation and in vitro evaluation of apigenin loaded lipid nanocapsules. Journal of Nanoscience and Nanotechnology. ,vol. 13, pp. 6546- 6552 ,(2013) , 10.1166/JNN.2013.7763
I. T. Shagautdinova, M. D. Elkin, A. M. Likhter, Identification of the vibrational spectra of apigenin and luteolin Journal of Surface Investigation. X-ray, Synchrotron and Neutron Techniques. ,vol. 9, pp. 753- 760 ,(2015) , 10.1134/S1027451015040175
Xin Zhao, Zhongni Wang, Xuepeng Li, Preparation, in-vitro release and antioxidant potential of formulation of apigenin with hydroxypropyl-β-cyclodextrin modified microemulsion Journal of Inclusion Phenomena and Macrocyclic Chemistry. ,vol. 86, pp. 93- 102 ,(2016) , 10.1007/S10847-016-0644-X
Yannian Huang, Yuangang Zu, Xiuhua Zhao, Mingfang Wu, Ziqi Feng, Yiping Deng, Chang Zu, Lingling Wang, Preparation of inclusion complex of apigenin-hydroxypropyl-β-cyclodextrin by using supercritical antisolvent process for dissolution and bioavailability enhancement. International Journal of Pharmaceutics. ,vol. 511, pp. 921- 930 ,(2016) , 10.1016/J.IJPHARM.2016.08.007
Maryvonne Steuck, Stefan Hellhake, Nils Helge Schebb, Food Polyphenol Apigenin Inhibits the Cytochrome P450 Monoxygenase Branch of the Arachidonic Acid Cascade Journal of Agricultural and Food Chemistry. ,vol. 64, pp. 8973- 8976 ,(2016) , 10.1021/ACS.JAFC.6B04501
Darshan R. Telange, Arun T. Patil, Anil M. Pethe, Harshal Fegade, Sridhar Anand, Vivek S. Dave, Formulation and characterization of an apigenin-phospholipid phytosome (APLC) for improved solubility, in vivo bioavailability, and antioxidant potential European Journal of Pharmaceutical Sciences. ,vol. 108, pp. 36- 49 ,(2017) , 10.1016/J.EJPS.2016.12.009
Manmohan Singh Jangdey, Anshita Gupta, Shailendra Saraf, Swarnlata Saraf, Development and optimization of apigenin-loaded transfersomal system for skin cancer delivery: in vitro evaluation. Artificial Cells Nanomedicine and Biotechnology. ,vol. 45, pp. 1452- 1462 ,(2017) , 10.1080/21691401.2016.1247850
Bożena Karolewicz, Maciej Gajda, Agata Górniak, Artur Owczarek, Igor Mucha, Pluronic F127 as a suitable carrier for preparing the imatinib base solid dispersions and its potential in development of a modified release dosage forms Journal of Thermal Analysis and Calorimetry. ,vol. 130, pp. 383- 390 ,(2017) , 10.1007/S10973-017-6139-1
Faiyaz Shakeel, Sultan Alshehri, Mohamed A Ibrahim, Ehab M Elzayat, Mohammad A Altamimi, Kazi Mohsin, Fars K Alanazi, Ibrahim A Alsarra, None, Solubility and thermodynamic parameters of apigenin in different neat solvents at different temperatures Journal of Molecular Liquids. ,vol. 234, pp. 73- 80 ,(2017) , 10.1016/J.MOLLIQ.2017.03.057
Mai Gamal Elhennawy, Hai-Shu Lin, Dose- and time-dependent pharmacokinetics of apigenin trimethyl ether. European Journal of Pharmaceutical Sciences. ,vol. 118, pp. 96- 102 ,(2018) , 10.1016/J.EJPS.2018.03.022