Postnatally induced formation of the corpus callosum in acallosal mice on glia-coated cellulose bridges

摘要: Developing axons of the corpus callosum mice are guided across cerebral midline by a slinglike glial structure that forms transiently between hemispheres. If "sling" is cut at precallosal stages, would-be callosal fibers whirl into paired neuromas adjacent to longitudinal fissure. In experiments on such surgically acallosal animals, aberrant commissural maintained potential regrow hemispheres prenatal and early postnatal stages if they were presented with properly aligned, glia-covered scaffold spanning