Specific inhibitors of MS2 and late T4 RNA translation in E. coli
作者： Sylvia Lee-Huang , Severo Ochoa
DOI: 10.1016/0006-291X(72)90420-2
关键词:
摘要: 1.0 M NH4Cl washes of E. coli ribosomes contain two protein factors affecting activities the polypeptide chain initiation factor 3 (IF3). One (iα) inhibits functions IF3α, IF3 species which recognizes MS2, coli, and early T4 RNA; other (iβ) IF3β, recognizing late RNA. Initiation complex formation translation mRNA are inhibited to same extent but ribosome dissociation activity is not affected.
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