Diagnosis of measles by clinical case definition in dengue-endemic areas: implications for measles surveillance and control.

作者: D J Gubler , V J Dietz , P Nieburg , I Gomez

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摘要: In many countries, measles surveillance relies heavily on the use of a standard clinical case definition; however, signs and symptoms are similar to those dengue. For example, during 1985, in Puerto Rico, 22 (23%) 94 cases illnesses with rashes that met definition were serologically confirmed as measles, but 32 (34%) others Retrospective analysis at San Juan Laboratories Centers for Disease Control showed also least 28% all laboratory-confirmed dengue Rico 1985 definition. If true vaccine efficacy (VE) is assumed be 90%, occurrence meet results reduction apparent VE only 64% (a 29% relative from VE). The study demonstrate importance laboratory-based system control or elimination efforts dengue-endemic areas.

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