Quantifying the effect of slice thickness, intravenous contrast and tube current on muscle segmentation: Implications for body composition analysis
作者： Georg Fuchs , Yves R. Chretien , Julia Mario , Synho Do , Matthias Eikermann
DOI: 10.1007/S00330-017-5191-3
关键词:
摘要: To quantify the effect of IV contrast, tube current and slice thickness on skeletal muscle cross-sectional area (CSA) density (SMD) routine CT. CSA SMD were computed 216 axial CT images obtained at L3 level in 72 patients with variations current. Intra-patient mean difference (MD), 95 % CI limits agreement calculated using Bland-Altman approach. Inter- intra-analyst was evaluated. contrast significantly increased by 1.88 (MD 2.33 cm2; 1.76–2.89) 5.99 (p<0.0001). Five mm 1.11 compared to 2 (1.32 0.78–1.85) decreased 11.64 Low 4.79 (6.44 3.78–9.10) 46.46 excellent. affect SMD. Investigators designing analysing clinical trials for body composition analysis should report acquisition parameters consider thickness, myometric data. • Intravenous Image parameter may obscure intrapatient differences serial measurements. parameters.
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