The Relationship Between Glycemic Response and the Incidence of OCD in Thoroughbred Weanlings: A Field Study

摘要: Hyperglycemia and hyperinsulinemia have been implicated in the pathogenesis of osteochondrosis (Glade et al., 1984; Ralston, 1995). More specifically, foals that experience an exaggerated sustained increase circulating glucose or insulin response to a carbohydrate (grain) meal may be predisposed development osteochondrosis. In vitro studies with fetal foal chondrocytes suggest role immature cartilage promote chondrocyte survival suppress differentiation contributory factor equine (Henson 1997). Rutgers University was recently granted United States patent for diagnosing predisposition osteochondritis dissecans (OCD) using oral tolerance test (United Patent). This based on premise exhibiting glycemic challenge were more susceptible developing OCD. The purpose present study evaluate if there is relationship between incidence OCD Thoroughbred weanlings, determine this would useful identifying factors predispose young growing horses