摘要: That ventilation in fish is driven by O2 has long been accepted. The ventilatory drive reflects the much lower capacitance of water for than CO2, and mediated receptors that are distributed throughout gill arches monitor both internal external levels. In recent years, however, evidence amassed support existence a keyed to CO2 and/or pH. While responses CO2/pH may be part through CO2/pH-induced changes blood status, also appear stimulate directly. involved this pathway as yet unknown, but experimental available date supports involvement branchial CO2-sensitive chemoreceptors with an orientation. Internally-oriented involved, although on point remains equivocal. present paper, CO2/pH-keyed will reviewed.