[Association between peripheral perfusion, microcirculation and mortality in sepsis: a systematic review].

摘要: Abstract Although increasing evidence supports the monitoring of peripheral perfusion in septic patients, no systematic review has been undertaken to explore strength association between poor assessed microcirculation tissues and mortality. A search most important databases was carried out find articles published until February 2018 that met criteria this study using different keywords: sepsis, mortality, prognosis, perfusion. The inclusion were studies perfusion/microcirculation mortality sepsis. exclusion adopted were: articles, animal/pre-clinical studies, meta-analyzes, abstracts, annals congress, editorials, letters, case-reports, duplicate did not present abstracts and/or had text. In 26 chosen which 2465 patients with sepsis evaluated at least one recognized method for demonstrated a heterogeneous critically ill group mortality-rate 3% 71% (median = 37% [28%–43%]). commonly used methods measurement Near-Infrared Spectroscopy (NIRS) (7 articles) Sidestream Dark-Field (SDF) imaging (5 articles). vascular bed studied sublingual/buccal (8 articles), followed by fingertip (4 majority (23 clear relationship conclusion, diagnosis hypoperfusion/microcirculatory abnormalities non-vital organs associated increased However, additional must be verify if can considered marker gravity or trigger factor organ failure