Skin and Soft Tissue Infections Due to Rapidly Growing Mycobacteria: Comparison of Clinical Features, Treatment, and Susceptibility

摘要: Objective To compare the demographics, clinical features, susceptibility patterns, and treatment for skin soft tissue infections due to Mycobacterium fortuitum chelonae or abscessus . Design Retrospective medical record review. Setting Mayo Clinic, Rochester, Minn. Patients All patients seen at our institution with a positive culture M , from sources between January 1, 1987, October 31, 2004. Main Outcome Measures Patient characteristics, therapeutic data, microbiological outcomes. Results The records of 63 rapidly growing mycobacteria were reviewed. older (61.5 vs 45.9 years, P  = .002) than tended manifest as single lesion (89% 38%, manifested multiple lesions (62% 11%, had prior invasive surgical procedure infected site (56% 27%,  = .04). more likely be taking immunosuppressive medications those (67% 30%,  = .006). Seven failed treatment, several whom immunocompromised comorbidities. Conclusions Skin are associated systemic comorbidities, including use medications. There significant differences in demographic features who acquire specific organisms, association immunosuppression procedures.