In-vivo demonstration of dopaminergic degeneration in dementia with Lewy bodies.
作者： Zuzana Walker , Durval C Costa , Paul Ince , lan G McKeith , Cornelius LE Katona
DOI: 10.1016/S0140-6736(99)01178-2
关键词:
摘要: With the dopaminergic presynaptic ligand FP-CIT and single photon emission tomography we have shown a severe degeneration in patient with necropsy confirmed diagnosis of dementia Lewy bodies (DLB). We suggest that functional imaging nigrostriatal dopamine pathway helps to distinguish DLB from Alzheimer's disease during life.
elsevier.com
sci-hub.se 参考文章(5)
Zuzana Walker, Durval C. Costa, Anthony G. Janssen, Rodney W. H. Walker, Gillian Livingstone, Cornelius L. E. Katona, Dementia with Lewy bodies: A study of post-synaptic dopaminergic receptors with iodine-123 iodobenzamide single-photon emission tomography European Journal of Nuclear Medicine and Molecular Imaging. ,vol. 24, pp. 609- 614 ,(1997) , 10.1007/BF00841397
J. William Langston, Hakan Widner, Christopher G. Goetz, David Brooks, Stanley Fahn, Thomas Freeman, Ray Watts, Core assessment program for intracerebral transplantations (CAPIT). Movement Disorders. ,vol. 7, pp. 2- 13 ,(1992) , 10.1002/MDS.870070103
M. Roth, E. Tym, C. Q. Mountjoy, F. A. Huppert, H. Hendrie, S. Verma, R. Goddard, CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. British Journal of Psychiatry. ,vol. 149, pp. 698- 709 ,(1986) , 10.1192/BJP.149.6.698
I.G. McKeith, D. Galasko, K. Kosaka, E.K. Perry, D.W. Dickson, L.A. Hansen, D.P. Salmon, J. Lowe, S.S. Mirra, E.J. Byrne, G. Lennox, N.P. Quinn, J.A. Edwardson, P.G. Ince, C. Bergeron, A. Burns, B.L. Miller, S. Lovestone, D. Collerton, E.N.H. Jansen, C. Ballard, R.A.I. de Vos, G.K. Wilcock, K.A. Jellinger, R.H. Perry, Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB) Report of the consortium on DLB international workshop Neurology. ,vol. 47, pp. 1113- 1124 ,(1996) , 10.1212/WNL.47.5.1113
Yesavage Ja, Geriatric Depression Scale. Psychopharmacology Bulletin. ,vol. 24, pp. 709- 711 ,(1988)