The effect of saturation with Zn2+ and other metal ions on the antibacterial activity of ovotransferrin.
作者： P. Valenti , P. Visca , G. Antonini , N. Orsi , E. Antonini
DOI: 10.1007/BF00193893
关键词:
摘要: The antibacterial activity of metal complexes ovotransferrin was tested “in vitro” against different bacterial species and the Zn2+ saturated appeared to be most active by comparison with apo-protein other complexes. Appropriate controls showed that such an effect neither due ions, nor iron deprivation, but a specific Zn-ovotransferrin complex. This required direct contact surface. In vivo experiments confirmed higher as compared apo-form.
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sci-hub.se 参考文章(21)
J W Donovan, K D Ross, Nonequivalence of the metal binding sites of conalbumin. Calorimetric and spectrophotometric studies of aluminum binding. Journal of Biological Chemistry. ,vol. 250, pp. 6022- 6025 ,(1975) , 10.1016/S0021-9258(19)41152-6
K M Lawlor, S M Payne, Aerobactin genes in Shigella spp. Journal of Bacteriology. ,vol. 160, pp. 266- 272 ,(1984) , 10.1128/JB.160.1.266-272.1984
R R Arnold, J E Russell, W J Champion, J J Gauthier, Bactericidal activity of human lactoferrin: influence of physical conditions and metabolic state of the target microorganism. Infection and Immunity. ,vol. 32, pp. 655- 660 ,(1981) , 10.1128/IAI.32.2.655-660.1981
B Colonna, M Nicoletti, P Visca, M Casalino, P Valenti, F Maimone, Composite IS1 elements encoding hydroxamate-mediated iron uptake in FIme plasmids from epidemic Salmonella spp. Journal of Bacteriology. ,vol. 162, pp. 307- 316 ,(1985) , 10.1128/JB.162.1.307-316.1985
P Valenti, G Antonini, M R Fanelli, N Orsi, E Antonini, Antibacterial activity of matrix-bound ovotransferrin. Antimicrobial Agents and Chemotherapy. ,vol. 21, pp. 840- 841 ,(1982) , 10.1128/AAC.21.5.840
A. T. Tan, Robert C. Woodworth, Ultraviolet difference spectrl studies of conalbumin complexes with transition metal ions. Biochemistry. ,vol. 8, pp. 3711- 3716 ,(1969) , 10.1021/BI00837A033
R. Arnold, M. Cole, McGhee, A bactericidal effect for human lactoferrin Science. ,vol. 197, pp. 263- 265 ,(1977) , 10.1126/SCIENCE.327545
Jerry L. Phillips, “Specific” binding of radioiodinated transferrin to polypropylene culture tubes Biochemical and Biophysical Research Communications. ,vol. 71, pp. 726- 732 ,(1976) , 10.1016/0006-291X(76)90891-3
Anthony W. Ford-Hutchinson, Deryck J. Perkins, The Binding of Scandium Ions to Transferrin in vivo and in vitro FEBS Journal. ,vol. 21, pp. 55- 59 ,(1971) , 10.1111/J.1432-1033.1971.TB01439.X
F. Gibson, D.I. Magrath, The isolation and characterization of a hydroxamic acid (aerobactin) formed by Aerobacter aerogenes 62-1 Biochimica et Biophysica Acta (BBA) - General Subjects. ,vol. 192, pp. 175- 184 ,(1969) , 10.1016/0304-4165(69)90353-5