Transdermal delivery of highly ionized fat insoluble drugs

作者: David James Enscore , Robert Martin Gale

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摘要: A medical device for the transdermal delivery of highly ionized, fat insoluble drugs comprises an aqueous drug reservoir having a physiological pH, said preferably being gel maintained in impermeable receptacle by permeable support member disposed between and contact adhesive. permeation enhancer delivers to skin through release rate controlling membrane which is water. In preferred embodiment forms at least portion receptacle.