Effect of ionizing radiation on rat tissue: proteomic and biochemical analysis.
作者： Eui‐Chul Park* , Jong‐Bok Yoon , Jin‐Sil Seong* , Kyoung‐Soo Choi , Eung‐Sik Kong
DOI: 10.1080/10826060500388470
关键词:
摘要: Abstract Reactive oxygen species (ROS), generated by ionizing radiation, has been implicated in its effect on living tissues. We confirmed the changes oxidative stress markers upon irradiation. characterized proteome profile rat liver after administering irradiation, and affected proteins were identified MALDI‐TOF‐MS ESI‐MS/MS. The represent diverse sets of participating cellular metabolism. Our results demonstrated that proteomics analysis is a useful method for characterization global change caused radiation to unravel molecular mechanisms involved responses radiation. *Equal contribution
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