Metabolic Bone Disease Following Organ Transplantation

摘要: A major debilitating consequence of organ transplant is acute rapid and severe bone loss (ARSBL), which results in an increased propensity to sustain a fracture. Multiple mechanisms for have been proposed glucocorticoid calcineurin inhibitor therapy are critical determinants high fracture risk. Additionally, preexisting renal, liver, heart disease also known cause different extents varieties disease, predispose the skeleton fragility even before transplantation. This chapter discusses concept post-transplant osteoporosis, its genesis, therapeutic modalities that could be used prevent loss.