Linkage Analysis in Nuclear Families. 2: Relationship between Affected Sib-Pair Tests and Lod Score Analysis

摘要: It is believed that the main advantage of affected sib-pair tests their application requires no information about underlying genetic mechanism disease. However, here it proved mean test, which can be considered most prominent tests, equivalent to lod score analysis for an assumed recessive mode inheritance, irrespective true Further relationships certain and under specific modes are investigated.