Synthesis of well-defined α,ω-telechelic multiblock copolymers in aqueous medium: in situ generation of α,ω-diols

摘要: The synthesis of well-defined α,ω-dihydroxyl telechelic multiblock copolymers by sequential in situ chain extensions via aqueous Cu(0) mediated living radical polymerization (SET-LRP) is reported. rapid disproportionation Cu(I)Br the presence Me6-TREN water has been exploited to generate and [Cu(II)Br2/Me6-TREN] situ, resulting reaction rate narrow molecular weight distributions. Under optimized conditions, a heptablock copolymer was obtained within 2 hours with final dispersity ∼1.1 while monomer conversion >99% for each block. A range acrylamides acrylates have successfully incorporated same polymer backbone, including N-isopropylacrylamide (NIPAAm), N,N-diethylacrylamide (DEA) N,N-dimethylacrylamide (DMA) poly(ethylene glycol) methyl ether acrylate (PEGA480). thermo-responsive nature these materials subsequently demonstrated cloud point measurements as both function backbone functionality. In addition, typically unwanted hydrolysis α- ω-end groups media further isocyanate post-polymerization modifications alter end group