Staging performance of whole-body DWI, PET/CT and PET/MRI in invasive ductal carcinoma of the breast

摘要: Abstract The aim of the present study was to evaluate performance whole-body diffusion-weighted imaging (WB-DWI), positron emission tomography with computed (WB-PET/CT), and magnetic resonance (WB-PET/MRI) in staging patients untreated invasive ductal carcinoma breast. Fifty-one women newly diagnosed breast underwent WB-DWI, WB-PET/CT WB-PET/MRI before treatment. A radiologist a nuclear medicine physician reviewed consensus images from three modalities searched for occurrence, number location metastases. Final staging, according each technique, compared. Pathology follow-up were used as reference. correctly concordantly staged 33/51 patients: stage IIA 7 patients, stage IIB 8 patients, stage IIIC 4 stage IV 14 patients. incorrectly 1/51 patient instead IIIA. Discordant reported 17/51 patients. resulted improved when compared (50 on vs. 38 WB-PET/CT; McNemar's test; p<0.01). Comparing WB-DWI (43 correct) did not reveal statistically significant difference (McNemar test, p=0.14). is more accurate initial cancer than WB-PET/CT, however, discrepancies between significant. When available, should be considered carcinoma.