Brain tumors in childhood and adolescence in west sweden 1970–1984 epidemiology and survival

作者: B. Lannering , I. Marky , C. Nordborg

DOI: 10.1002/1097-0142(19900801)66:3<604::AID-CNCR2820660334>3.0.CO;2-L

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摘要: A population-based series of 198 children, aged 0 to 16.9 years, with primary brain tumors, diagnosed from 1970 1984, was retrieved the Swedish Cancer Registry. After review slides and reclassification histology according American Society, average annual incidence rate estimated be 34.9 per million, which is a very high compared other countries. The age distribution not uniform as group 4 included more children than groups 5 9 10 14. largest subgroups were astrocytomas (25%) primitive neuroectodermal tumor (PNET)/medulloblastomas (MB) (21%). Associated diseases neurofibromatosis Rubinstein-Taybi syndrome. overall male female ratio 1.08:1, same in population at risk; but for PNET/MB, it 1.8:1. 5-year survival all tumors 54%, 15-year survival, 49%, great variation between subgroups.

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