Chapter 8 Fear and anxiety mechanisms of the brain: Clinical implications

摘要: Summary Our understanding of the neurobiology human fears has emerged largely from basic research on brains “lower” animals. Evidence behavioral neuroscience strongly suggests that unconditional (innate) capacity to experience fear, along with fear-typical patterns autonomic and arousal, emerge specific systems brain—the most prominent being a FEAR circuit, which courses between amygdala central gray midbrain. Fear behaviors can be evoked by artificially activating this response is coordinated experiential effects. The neurochemical controls emotional system include variety neuropeptides modulate anxiety. Minor tranquilizers benzodiazepine (BZ) class work, in part, dampening activity through increased GABA-mediated neural inhibition. traditional use minor control clinical anxiety also summarized.